Projects and Labs
Circulating Tumor Cells for Cancer Diagnosis and Prognosis
Early detection of cancer and monitoring of cancer therapy are critical in increasing the chances of survival. The CBRP is developing and testing an innovative instrument and method to greatly improve both the early detection of breast cancer and help improve disease progression monitoring. This will be accomplished by developing a new laser scanning based technology which has the ability to identify tumor cells in breast cancer patient blood.
JCIMPT: JCSG Center for Innovative Membrane Protein Technologies
The mission of JCIMPT is to develop and disseminate methods and technolgies for structure-grade production of integral membrane proteins. Miniaturization and automation are major components in the systematic investigation of membrane proteins and in the development of novel genetically engineered expression systems and sample preparation technologies. The structure of the JCIMPT includes three primary projects: Membrane Protein Expression; Membrane Protein Stablization; and Membrane Protein Biophysical Analysis.
C-ME: Collaborative Molecular Modelling Environment:
In collaboration with Interknowlogy, LLC (Carlsbad, CA) and support from Microsoft, Inc., we have developed and are further improving a software client named C-ME to enable improved collaboration among scientists. C-ME uses the latest Microsoft technologies, Vista, Office 2007 and Sharepoint 2007.
FSPS: Functional and Structural Proteomics of SARS-CoV related proteins
The goal of FSPS is to provide a comprehensive molecular characterization and cataloging of all SARS-CoV proteins as well as associated functions at the viral and host levels. Complete understanding of the SARS-CoV proteins will enable the development of therapeutic interventions for the virus.
ATCG3D: Accelerated Technologies Center for Gene to 3D structure
The Accelerated Technologies Center for Gene to 3D structure project aims to use innovate methods to characterize the structure-function relationship of proteins. The path from gene to structure poses many challenges and ATCG3D aims to address these obstacles by using integrated instruments, methods, and software to increase sucess rate while reducing time, effort, and cost required for protein structure determination.