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Kuhn Lab at The Scripps Research Institute.
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Publications:

Mutations in LOXHD1, an Evolutionarily Conserved Stereociliary Protein, Disrupt Hair Cell Function in Mice and Cause Progressive Hearing Loss in HumansUse SHIFT+ENTER to open the menu (new window).
PDFNicolas Grillet et al.AJHG9/4/2009
Circulating tumor cells from well-differentiated lung adenocarcinoma retain cytomorphologic features of primary tumor type: A case study Use SHIFT+ENTER to open the menu (new window).
PDFMarrinucci D. et al. Archives of Pathology and Laboratory Medicine9/2/2009
Current Opinion in MicrobiologyUse SHIFT+ENTER to open the menu (new window).
LinkPeter Kuhn, Issue EditorCurrent Opinion in Microbiology1/15/2009
Structural Basis of Guanine Nucleotide Exchange Mediated by the T-cell Essential Vav1Use SHIFT+ENTER to open the menu (new window).
ArticleChrencik, J.E., Brooun, A., Zhang, H., Mathews, I.I., Hura, G.L., Foster, S.A., Perry, J.J.P., Streiff, M., Ramage, P., Widmer, H., Bokoch, G.M., Tainer, J., Weckbecker, G. & Kuhn, P.Journal of Molecular Biology5/17/2008
Enthalpy array analysis of enzymatic and binding reactions Use SHIFT+ENTER to open the menu (new window).
LinkRecht, M.I., De Bruyker, D., Bell, A.G., Wolkin, M.V., Peeters, E., Anderson, G.B., Kolatkar, A.R., Bern, M.W., Kuhn, P., Bruce, R.H., Torres, F.E.Analytical biochemistry4/28/2008
Proteomics Analysis Unravels the Functional Repertoire of Coronavirus Nonstructural Protein 3Use SHIFT+ENTER to open the menu (new window).
PubMed EntryNeuman, B.W., Joseph, J.S., Saikatendu, K.S., Serrano, P., Chatterjee, A., Johnson, M.A., Liao, L., Klaus, J.P.,Journal of Virology3/16/2008
C-ME: A 3D Community-Based, Real-Time Collaboration Tool for Scientific Research and Training Use SHIFT+ENTER to open the menu (new window).
http://www.plosone.org/doi/pone.0001621Kolatkar, A., Kennedy, K., Halabuk, D., Kunken, J., Marrinucci, D., Bethel, K., Guzman, R., Huckaby, T., Kuhn, P.PLoS ONE2/20/2008
Automated Data Acquisition through Microsoft Office SharePoint Server 2007 facilitated using PowerShellUse SHIFT+ENTER to open the menu (new window).
URLKunken, Jcodeproject.com1/8/2008
Three-dimensional Structure of the EphB2 Receptor in Complex with an Antagonistic Peptide Reveals a Novel Mode of Inhibition Use SHIFT+ENTER to open the menu (new window).
PubMed EntryChrencik JE, et al.  Journal of Biological Chemistry  12/14/2007
International research networks in viral structural proteomics: Again, lessons from SARS.Use SHIFT+ENTER to open the menu (new window).
Pubmed EntryCanard, B., Joseph, J.S., Kuhn, P.Antiviral Res 12/1/2007
Clathrate nanostructures for mass spectrometryUse SHIFT+ENTER to open the menu (new window).
Northen, T., Yanes, O., Northen, T., Marrinucci, D., Uritboonthai, W., Apon, J., Golledge, S., Nordstrom, A., Siuzdak, G.Nature10/25/2007
High-Resolution Crystal Structure of an Engineered Human {beta}2-Adrenergic G Protein–Coupled ReceptorUse SHIFT+ENTER to open the menu (new window).
PDFCherezov, V., Rosenbaum, D., Hanson, M., Rasmussen, S., Thian, F., Kobilka, T., Choi, H., Kuhn, P., Weis, W., Kobilka, B., Stevens, R.Science10/25/2007
Automated N-glycopeptide Identification Using a Combination of Single- and Tandem-MSUse SHIFT+ENTER to open the menu (new window).
PubMed EntryGoldberg, D., Bern, M., Parry, S., Sutton-Smith, M., Panico, M., Morris, H., Dell, A.J. Proteome Res10/15/2007
Improved Ranking Functions for Protein and Modification-Site IdentificationsUse SHIFT+ENTER to open the menu (new window).
PubMed EntryBern, M., Goldberg, D.11th International Conference on Research in Computational Molecular Biology, RECOMB 200710/15/2007
Crystal structure of a monomeric form of SARS-CoV endonuclease nsp15 suggests a role for hexamerization as an allosteric switchUse SHIFT+ENTER to open the menu (new window).
LinkJoseph JS, et al.Journal of Virology2/27/2007
Five years of increasing structural biology throughput. A retrospective analysisUse SHIFT+ENTER to open the menu (new window).
Abola E, et al.Structure Based Drug Discovery2/27/2007
Protein crystallization in restricted geometry: advancing old ideas for modern times in structural proteomicsUse SHIFT+ENTER to open the menu (new window).
Ng JD et al.Methods in Molecular Biology2/27/2007
Lookup Peaks: A Hybrid of de Novo Sequencing and Database Search for Protein Identification by Tandem Mass SpectrometryUse SHIFT+ENTER to open the menu (new window).
Bern, M., Cai, Y., Goldberg, D.Anal. Chem.2/26/2007
Glycoproteomics: Past, Present, and FutureUse SHIFT+ENTER to open the menu (new window).
Morris, H., Chalabi, S., Panico, M., Sutton-Smith, M., Clark, G., Goldberg, D., Dell, A.Mass Spectrometry1/26/2007
Ribonucleocapsid formation of SARS-CoV through molecular action of the N-terminal domain of N protein.Use SHIFT+ENTER to open the menu (new window).
PubMed EntrySaikatendu KS, et al.Journal of Virology1/17/2007
Novel beta-barrel fold in the nuclear magnetic resonance structure of the replicase nonstructural protein 1 from the severe acute respiratory Use SHIFT+ENTER to open the menu (new window).
PDFAlmeida M et al.J. Virol.1/1/2007
Case study of the morphologic variation of circulating tumor cells.Use SHIFT+ENTER to open the menu (new window).
PubMed EntryMarrinucci D, et al.Human Pathology12/21/2006
Molecular evolution of antibody cross-reactivity for two subtypes of type A botulinum neurotoxinUse SHIFT+ENTER to open the menu (new window).
DOI:10.1038/nbt1269Garcia-Rodriguez C, et al.Nature Biotechnology12/17/2006
Structural basis of cell surface receptor recognition by botulinum neurotoxin BUse SHIFT+ENTER to open the menu (new window).
DOI:10.1038/nature05411Chai Q, et al.Nature12/13/2006
Time-Controlled Microfluidic Seeding in nL-Volume Droplets to Separate Nucleation and Growth Stages of Protein CrystallizationUse SHIFT+ENTER to open the menu (new window).
DOI:10.1038/nature05411Gerdts CJ, et al  Angewandte Chemie Int. Ed Engl.12/11/2006
Remedial strategies in structural proteomics: Expression, purification, and crystallization of the Vav1/Rac1 complex.Use SHIFT+ENTER to open the menu (new window).
PubMed EntryBrooun A., et al.Protein Expr Purif.12/5/2006
A PAH Gene Knowledgebase: Content, Informatics, UtilizationUse SHIFT+ENTER to open the menu (new window).
Scriver CR, et al.PKU and BH4: Advances in Phenylketonuria and Tetrahydrobiopterin Research12/1/2006
SPINE ForwardUse SHIFT+ENTER to open the menu (new window).
Stevens RCActa Crystallogr.12/1/2006
Comparative structural analysis of a novel glutathione S-transferase (ATU5508) from Agrobacterium tumefaciens at 2.0 Å resolution.Use SHIFT+ENTER to open the menu (new window).
DOI:10.1002/prot.21130Kosloff M, et al.Proteins11/15/2006
Crystal structure of 2-phosphysulfolactate phosphatase (ComB) from Clostridium acetobutylicum at 2.6 Å resolution reveals a new fold with a novel active siteUse SHIFT+ENTER to open the menu (new window).
DOI:10.1002/prot.20978DiDonato M, et al.Proteins11/15/2006
Crystal structure of an ORFan protein (TM1622) from Thermotoga maritima at 1.75 Å resolution reveals a fold similar to the Ran-binding protein Mog1pUse SHIFT+ENTER to open the menu (new window).
DOI:10.1002/prot.21015Xu Q, et al.Proteins11/15/2006
Activation of Murine CD4+ and CD8+ T Lymphocytes Leads to Dramatic Remodeling of N-Linked GlycansUse SHIFT+ENTER to open the menu (new window).
PubMed EntryComelli, E., Sutton-Smith, M., Yan, Q., Amado, M., Panico, M., Gilmartin, T., Whisenant, T., Lanigan, C., Head, S., Goldberg, D., Morris, H., Dell, A., Paulson, J.Journal of Immunology10/26/2006
Automatic Determination of O-Glycan Structure from Fragmentation SpectraUse SHIFT+ENTER to open the menu (new window).
PubMed EntryGoldberg, D., Bern, M., Li, B. Lebrilla, C.Journal of Proteome Research10/26/2006
Data Mining for Proteins Characteristic of CladesUse SHIFT+ENTER to open the menu (new window).
PubMed EntryBern, M., Goldberg, D., and Lyashenko, E.Nucleic Acids Research10/26/2006
De Novo Analysis of Peptide Tandem Mass Spectra by Spectral Graph PartitioningUse SHIFT+ENTER to open the menu (new window).
Bern, M. and Goldberg, D.Journal of Computational Biology10/26/2006
C-ME: a smart client to enable collaboration using a two- or three-dimensional contextual basis for annotations.Use SHIFT+ENTER to open the menu (new window).
http://www.mscs06.net/agenda.asp?#5CAnand KolatkarMicrosoft eScience Workshop (October 13-15, 2006)10/15/2006
Crystal structure of a glycerate kinase (TM1585) from Thermotoga maritima at 2.70 Å resolution reveals a new foldUse SHIFT+ENTER to open the menu (new window).
DOI:10.1002/prot.21058Schwarzenbacher R, et al.Proteins10/1/2006
Crystal structure of phosphoribosylformyl-glycinamidine synthase II, PurS subunit (TM1244) from Thermotoga maritima at 1.90 Å resolutionUse SHIFT+ENTER to open the menu (new window).
DOI:10.1002/prot.21024Mathews II, et al.Proteins10/1/2006
A structural perspective of the sequence variability within botulinum neurotoxin subtypes A1-A4Use SHIFT+ENTER to open the menu (new window).
DOI:10.1016/j.jmb.2006.07.040Arndt JW, et al.J. Mol. Biol.9/29/2006
Structural and Biophysical Characterization of the EphB4-EphrinB2 Protein-Protein Interaction and Receptor SpecificityUse SHIFT+ENTER to open the menu (new window).
PubMed EntryChrencik JE, et al.Journal of Biological Chemistry9/22/2006
Crystal structure of the ApbE protein (TM1553) from Thermotoga maritima at 1.58 Å resolutionUse SHIFT+ENTER to open the menu (new window).
DOI:10.1002/prot.20950Han GW, et al.Proteins9/1/2006
Miniaturization of the structural biology technologies – From expression to biophysical analysesUse SHIFT+ENTER to open the menu (new window).
Abola E, et al.Structural Genomics on Membrane Proteins.9/1/2006
Crystal structure of acireductone dioxygenase (ARD) from Mus musculus at 2.06 Å resolutionUse SHIFT+ENTER to open the menu (new window).
DOI:10.1002/prot.20947Xu Q, et al.Proteins8/15/2006
Crystal structure of nonstructural protein 10 from the severe acute respiratory syndrome coronavirus reveals a novel fold with two zinc-binding motifs.Use SHIFT+ENTER to open the menu (new window).
DOI:10.1128/JVI.00467-06Joseph J.S. et alJournal of Virology8/7/2006
Supramolecular architecture of severe acute respiratory syndrome coronavirus revealed by electron cryomicroscopy.Use SHIFT+ENTER to open the menu (new window).
PubMed EntryNeuman BW. et al.Journal of Virology8/7/2006
Crystal structure of phosphoribosylformylglycinamidine synthase II (smPurL) from Thermotoga maritima at 2.15 A resolutionUse SHIFT+ENTER to open the menu (new window).
DOI:10.1002/prot.20650Mathews II, et al.Proteins6/1/2006
Crystal structure of TM1367 from Thermotoga maritima at 1.90 A resolution reveals an atypical member of the cyclophilin (peptidylprolyl isomerase) foldUse SHIFT+ENTER to open the menu (new window).
DOI:10.1002/prot.20894Jin KK, et al.Proteins6/1/2006
High speed detection of circulating tumor cellsUse SHIFT+ENTER to open the menu (new window).
PDFHsieh H.B et al.Biosensors and Bioelectronics5/7/2006
Collaboration on Steroids with WPF, Office 2007, and Sharepoint 2007. Communicating and curing CancerUse SHIFT+ENTER to open the menu (new window).
http://dotnet.sys-con.com/read/204815.htmRodney Guzman.NET Developer's Journal (On-line)4/19/2006
Severe acute respiratory syndrome coronavirus papain-like protease: structure of a viral deubiquitinating enzymeUse SHIFT+ENTER to open the menu (new window).
DOI:10.1073/pnas.0510851103Ratia K, et al.Proc. Nat. Acad. Sci. 4/11/2006
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